David Church

Latest

• Comprehensive Repertoire of the Chromosomal Alteration and Mutational Signatures across 16 Cancer Types from 10,983 Cancer Patients.
• Whole Genome Sequencing of 2,023 Colorectal Cancers Reveals Mutational Landscapes, New Driver Genes and Immune Interactions
• Germline MBD4 Deficiency Causes a Multi-Tumor Predisposition Syndrome
• Germline Loss-of-Function Variants in the Base-Excision Repair Gene MBD4 Cause a Mendelian Recessive Syndrome of Adenomatous Colorectal Polyposis and Acute Myeloid Leukaemia
• Promises and Challenges of Adoptive T-Cell Therapies for Solid Tumours