David J Adams

Latest

• Uncovering Novel Mutational Signatures by de Novo Extraction with SigProfilerExtractor
• Germline MBD4 Deficiency Causes a Multi-Tumor Predisposition Syndrome
• Germline Loss-of-Function Variants in the Base-Excision Repair Gene MBD4 Cause a Mendelian Recessive Syndrome of Adenomatous Colorectal Polyposis and Acute Myeloid Leukaemia
• Characterizing Genetic Intra-Tumor Heterogeneity across 2,658 Human Cancer Genomes
• Multi-Site Clonality Analysis Uncovers Pervasive Heterogeneity across Melanoma Metastases
• Abstract 3000: Pervasive Intra-Tumour Heterogeneity and Subclonal Selection across Cancer Types
• The Genetic Heterogeneity and Mutational Burden of Engineered Melanomas in Zebrafish Models