Inigo Martincorena

Latest

• Uncovering Novel Mutational Signatures by de Novo Extraction with SigProfilerExtractor
• The Architecture of Clonal Expansions in Morphologically Normal Tissue from Cancerous and Non-Cancerous Prostates
• Characterizing Genetic Intra-Tumor Heterogeneity across 2,658 Human Cancer Genomes
• Genomic Evidence Supports a Clonal Diaspora Model for Metastases of Esophageal Adenocarcinoma
• Embryonal Precursors of Wilms Tumor
• Genomic Landscape and Chronological Reconstruction of Driver Events in Multiple Myeloma
• Neutral Tumor Evolution?
• The Genomic Landscape of Structural Variations and Complex Events in Multiple Myeloma
• Analysis of Mutations and Structural Variants to Redefine the Genomic Landscape of Multiple Myeloma and Its Clinical Implications
• Genomic Patterns of Progression in Smoldering Multiple Myeloma
• Abstract 3000: Pervasive Intra-Tumour Heterogeneity and Subclonal Selection across Cancer Types
• PO-329 Rejecting Neutral Tumour Evolution across Human Cancer Types
• Sequencing of Prostate Cancers Identifies New Cancer Genes, Routes of Progression and Drug Targets
• Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal
• Pan-Cancer Analysis of Whole Genomes Reveals Driver Rearrangements Promoted by LINE-1 Retrotransposition in Human Tumours
• The Genomic Landscape of Multiple Myeloma Complex Structural Variations
• Genomic Evolution of Breast Cancer Metastasis and Relapse
• Recurrent Mutation of IGF Signalling Genes and Distinct Patterns of Genomic Rearrangement in Osteosarcoma
• Somatic Mutations Reveal Asymmetric Cellular Dynamics in the Early Human Embryo
• 651 - Whole Genome Sequencing of Unique Paired Smm-Mgus Progressing to Mm Samples Reveals a Genomic Landscape with Diverse Evolutionary Pattern
• Analysis of Mutational Signatures Suggest That Aid Has an Early and Driver Role in Multiple Myeloma
• The Complex Landscape of Rearrangements in Smoldering and Symptomatic Multiple Myeloma Revealed By Whole-Genome Sequencing
• Landscape of Somatic Mutations in 560 Breast Cancer Whole-Genome Sequences
• High Burden and Pervasive Positive Selection of Somatic Mutations in Normal Human Skin
• Extensive Transduction of Nonrepetitive DNA Mediated by L1 Retrotransposition in Cancer Genomes
• Genome Sequencing of Normal Cells Reveals Developmental Lineages and Mutational Processes
• Recurrent PTPRB and PLCG1 Mutations in Angiosarcoma
• Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage
• Heterogeneity of Genomic Evolution and Mutational Profiles in Multiple Myeloma
• RAG-Mediated Recombination Is the Predominant Driver of Oncogenic Rearrangement in ETV6-RUNX1 Acute Lymphoblastic Leukemia
• Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
• The Genetic Heterogeneity and Mutational Burden of Engineered Melanomas in Zebrafish Models
• 651 - Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution
• The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients