Michael R Stratton

Latest

• Uncovering Novel Mutational Signatures by de Novo Extraction with SigProfilerExtractor
• Evolution and Lineage Dynamics of a Transmissible Cancer in Tasmanian Devils
• Genomic Evidence Supports a Clonal Diaspora Model for Metastases of Esophageal Adenocarcinoma
• Embryonal Precursors of Wilms Tumor
• Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis
• Pan-Cancer Analysis of Homozygous Deletions in Primary Tumours Uncovers Rare Tumour Suppressors
• Genomic Evolution of Breast Cancer Metastasis and Relapse
• Recurrent Mutation of IGF Signalling Genes and Distinct Patterns of Genomic Rearrangement in Osteosarcoma
• Somatic Mutations Reveal Asymmetric Cellular Dynamics in the Early Human Embryo
• Mutational Signatures of Ionizing Radiation in Second Malignancies
• Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
• Landscape of Somatic Mutations in 560 Breast Cancer Whole-Genome Sequences
• Clock-like Mutational Processes in Human Somatic Cells
• Subclonal Diversification of Primary Breast Cancer Revealed by Multiregion Sequencing
• High Burden and Pervasive Positive Selection of Somatic Mutations in Normal Human Skin
• Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue
• Combined Hereditary and Somatic Mutations of Replication Error Repair Genes Result in Rapid Onset of Ultra-Hypermutated Cancers
• Extensive Transduction of Nonrepetitive DNA Mediated by L1 Retrotransposition in Cancer Genomes
• Genome Sequencing of Normal Cells Reveals Developmental Lineages and Mutational Processes
• Genomic Heterogeneity in Primary Breast Cancer: Clinical Implications.
• Association of a Germline Copy Number Polymorphism of APOBEC3A and APOBEC3B with Burden of Putative APOBEC-Dependent Mutations in Breast Cancer
• Recurrent PTPRB and PLCG1 Mutations in Angiosarcoma
• Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage
• RAG-Mediated Recombination Is the Predominant Driver of Oncogenic Rearrangement in ETV6-RUNX1 Acute Lymphoblastic Leukemia
• Clinical and Biological Implications of Driver Mutations in Myelodysplastic Syndromes
• Distinct H3F3A and H3F3B Driver Mutations Define Chondroblastoma and Giant Cell Tumor of Bone
• The Landscape of Tumor Suppressors across Human Cancers
• Signatures of Mutational Processes in Human Cancer
• Whole Exome Sequencing of Adenoid Cystic Carcinoma
• Frequent Mutation of the Major Cartilage Collagen Gene COL2A1 in Chondrosarcoma
• ETV6-RUNX1 ALL, INSIGHTS FROM INTEGRATIVE GENOMIC ANALYSIS
• Deciphering Signatures of Mutational Processes Operative in Human Cancer
• Mutational Processes Molding the Genomes of 21 Breast Cancers
• The Life History of 21 Breast Cancers
• The Landscape of Cancer Genes and Mutational Processes in Breast Cancer
• Exploring the Subclonal Architecture of Breast Cancer
• Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer
• Tandem Duplication of Chromosomal Segments Is Common in Ovarian and Breast Cancer Genomes