Peter Van Loo

Latest

• Cancer Origin Tracing and Timing in Two High-Risk Prostate Cancers Using Multisample Whole Genome Analysis: Prospects for Personalized Medicine
• Crowd-Sourced Benchmarking of Single-Sample Tumour Subclonal Reconstruction
• Whole-Genome Analysis of Nigerian Patients with Breast Cancer Reveals Ethnic-Driven Somatic Evolution and Distinct Genomic Subtypes
• Characterizing Genetic Intra-Tumor Heterogeneity across 2,658 Human Cancer Genomes
• Promises and Challenges of Adoptive T-Cell Therapies for Solid Tumours
• A Practical Guide to Cancer Subclonal Reconstruction from DNA Sequencing
• DNA Copy Number Motifs Are Strong and Independent Predictors of Survival in Breast Cancer
• The Evolutionary History of 2,658 Cancers
• A Community Effort to Create Standards for Evaluating Tumor Subclonal Reconstruction
• Abstract LB-300: The Life History of Breast Cancer in Nigerian Women: Evidence for Ethnic Differences in Tumor Evolution Based on Whole-Genome Sequencing
• Time Series Analysis of Neoadjuvant Chemotherapy and Bevacizumab-Treated Breast Carcinomas Reveals a Systemic Shift in Genomic Aberrations
• Neutral Tumor Evolution?
• Abstract 3000: Pervasive Intra-Tumour Heterogeneity and Subclonal Selection across Cancer Types
• 33 PAN-Cancer Whole Genome Sequencing Reveals Patterns of Subclonal Mutations, Signature Changes and Selection
• PO-329 Rejecting Neutral Tumour Evolution across Human Cancer Types
• Sequencing of Prostate Cancers Identifies New Cancer Genes, Routes of Progression and Drug Targets
• Pan-Cancer Analysis of Whole Genomes Reveals Driver Rearrangements Promoted by LINE-1 Retrotransposition in Human Tumours
• Pan-Cancer Analysis of Homozygous Deletions in Primary Tumours Uncovers Rare Tumour Suppressors
• Appraising the Relevance of DNA Copy Number Loss and Gain in Prostate Cancer Using Whole Genome DNA Sequence Data
• Genomic Evolution of Breast Cancer Metastasis and Relapse
• Principles of Reconstructing the Subclonal Architecture of Cancers
• Recurrent Mutation of IGF Signalling Genes and Distinct Patterns of Genomic Rearrangement in Osteosarcoma
• How Subclonal Modeling Is Changing the Metastatic Paradigm
• Tracing the Origin of Disseminated Tumor Cells in Breast Cancer Using Single-Cell Sequencing
• ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data
• Mutational Signatures of Ionizing Radiation in Second Malignancies
• The Genomic Landscape of Pancreatic and Periampullary AdenocarcinomaCopy Number Aberrations in Periampullary Adenocarcinomas
• Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
• Abstract LB-337: Systemic Shift in Genomic Aberrations in Breast Carcinomas during Neoadjuvant Chemotherapy in Combination with Bevacizumab
• 361 - Genomic Evolution and Heterogeneity in 2,800 Cancers
• Landscape of Somatic Mutations in 560 Breast Cancer Whole-Genome Sequences
• Rapid Parallel Acquisition of Somatic Mutations after NPM1 in Acute Myeloid Leukaemia Evolution
• Abstract B09: DNA Polymerase Mutations Trigger Rapid Onset of Ultra-Hypermutant Malignant Brain Tumors in Children with Biallelic Mismatch Repair Deficiency
• Abstract LB-051: Tumor Heterogeneity and Dissemination in Breast Cancer: Deep Sequencing of Single Disseminated Cells from Bone Marrow Compared to Primary Tumor and Lymph Node Metastases
• Clonal Evolution of a Lethal Prostate Cancer: Integrated Whole Genome Analysis Case Study
• Subclonal Diversification of Primary Breast Cancer Revealed by Multiregion Sequencing
• High Burden and Pervasive Positive Selection of Somatic Mutations in Normal Human Skin
• 168 Evolution of Copy Number Aberrations with Time and Gleason Grade in Localised Prostate Cancer
• The Evolutionary History of Lethal Metastatic Prostate Cancer
• Tracking the Origins and Drivers of Subclonal Metastatic Expansion in Prostate Cancer
• Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue
• Tracking Clonal Diversity in Metastatic Prostate Cancer Progression.
• Combined Hereditary and Somatic Mutations of Replication Error Repair Genes Result in Rapid Onset of Ultra-Hypermutated Cancers
• Diagnostic Value of H3F3A Mutations in Giant Cell Tumour of Bone Compared to Osteoclast-Rich Mimics
• Differential and Limited Expression of Mutant Alleles in Multiple Myeloma
• Spatial and Temporal Diversity in Genomic Instability Processes Defines Lung Cancer Evolution
• Extensive Transduction of Nonrepetitive DNA Mediated by L1 Retrotransposition in Cancer Genomes
• Genomic Heterogeneity in Primary Breast Cancer: Clinical Implications.
• MP49-01 SUBCLONAL ORIGIN OF PROSTATE CANCER METASTASIS WITH MUTATOR PHENOTYPE FROM A NOVEL MSH2 GENE FUSION
• MP49-06 GENOMIC ANALYSIS OF MULTIPLE PROSTATE CANCER METASTASES HIGHLIGHTS METASTASIS FROM LOW-GRADE CANCER FOCI AND DYNAMIC ADAPTATIONS TO THERAPY
• Recurrent PTPRB and PLCG1 Mutations in Angiosarcoma
• Heterogeneity of Genomic Evolution and Mutational Profiles in Multiple Myeloma
• RAG-Mediated Recombination Is the Predominant Driver of Oncogenic Rearrangement in ETV6-RUNX1 Acute Lymphoblastic Leukemia
• Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
• The Genetic Heterogeneity and Mutational Burden of Engineered Melanomas in Zebrafish Models
• Clinical and Biological Implications of Driver Mutations in Myelodysplastic Syndromes
• 651 - Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution
• The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients
• Distinct H3F3A and H3F3B Driver Mutations Define Chondroblastoma and Giant Cell Tumor of Bone
• The Landscape of Tumor Suppressors across Human Cancers
• Whole Exome Sequencing of Adenoid Cystic Carcinoma
• Frequent Mutation of the Major Cartilage Collagen Gene COL2A1 in Chondrosarcoma
• Kataegis and Other Somatic Mutational Signatures in Cancer
• ETV6-RUNX1 ALL, INSIGHTS FROM INTEGRATIVE GENOMIC ANALYSIS
• 604 Cancer Genomics, Epigenetics and Genomic Instability. Mutational Processes Shaping the Genomes of Twenty-One Breast Cancers
• Mutational Processes Molding the Genomes of 21 Breast Cancers
• The Life History of 21 Breast Cancers
• The Landscape of Cancer Genes and Mutational Processes in Breast Cancer
• Exploring the Subclonal Architecture of Breast Cancer