Richard S Houlston

Latest

• Genomic Landscape of Diffuse Glioma Revealed by Whole Genome Sequencing
• Cancer Driver Genes and Opportunities for Precision Oncology Revealed by Whole Genome Sequencing 10,478 Cancers
• Comprehensive Repertoire of the Chromosomal Alteration and Mutational Signatures across 16 Cancer Types from 10,983 Cancer Patients.
• Whole Genome Sequencing of 2,023 Colorectal Cancers Reveals Mutational Landscapes, New Driver Genes and Immune Interactions
• Germline MBD4 Deficiency Causes a Multi-Tumor Predisposition Syndrome
• Germline Loss-of-Function Variants in the Base-Excision Repair Gene MBD4 Cause a Mendelian Recessive Syndrome of Adenomatous Colorectal Polyposis and Acute Myeloid Leukaemia
• Reference Bias in the Illumina Isaac Aligner
• Correcting Reference Bias from the Illumina Isaac Aligner Enables Analysis of Cancer Genomes
• The Preliminary Results from the 100,000 Genomes Project: The Genomic Landscape of Colorectal Cancer