Serena Nik-Zainal

Latest

• Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis
• Somatic Mutations Reveal Asymmetric Cellular Dynamics in the Early Human Embryo
• ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data
• Analysis of Mutational Signatures Suggest That Aid Has an Early and Driver Role in Multiple Myeloma
• Mutational Signatures of Ionizing Radiation in Second Malignancies
• Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
• Landscape of Somatic Mutations in 560 Breast Cancer Whole-Genome Sequences
• Clock-like Mutational Processes in Human Somatic Cells
• Subclonal Diversification of Primary Breast Cancer Revealed by Multiregion Sequencing
• Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue
• Extensive Transduction of Nonrepetitive DNA Mediated by L1 Retrotransposition in Cancer Genomes
• Association of a Germline Copy Number Polymorphism of APOBEC3A and APOBEC3B with Burden of Putative APOBEC-Dependent Mutations in Breast Cancer
• Heterogeneity of Genomic Evolution and Mutational Profiles in Multiple Myeloma
• RAG-Mediated Recombination Is the Predominant Driver of Oncogenic Rearrangement in ETV6-RUNX1 Acute Lymphoblastic Leukemia
• The Genetic Heterogeneity and Mutational Burden of Engineered Melanomas in Zebrafish Models
• 651 - Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution
• Distinct H3F3A and H3F3B Driver Mutations Define Chondroblastoma and Giant Cell Tumor of Bone
• Signatures of Mutational Processes in Human Cancer
• Whole Exome Sequencing of Adenoid Cystic Carcinoma
• Frequent Mutation of the Major Cartilage Collagen Gene COL2A1 in Chondrosarcoma
• Kataegis and Other Somatic Mutational Signatures in Cancer
• AID-APOBEC Cytidine Deaminases Can Mimic the Phenomenon of Localized Hypermutation in Cancer or Kataegis.
• Deciphering Signatures of Mutational Processes Operative in Human Cancer
• 604 Cancer Genomics, Epigenetics and Genomic Instability. Mutational Processes Shaping the Genomes of Twenty-One Breast Cancers
• Mutational Processes Molding the Genomes of 21 Breast Cancers
• The Life History of 21 Breast Cancers
• The Landscape of Cancer Genes and Mutational Processes in Breast Cancer
• Exploring the Subclonal Architecture of Breast Cancer