AmplificationTimeR

AmplificationTimeR is an R based tool that is designed to time individual copy number gain events up to a maximum copy number of 10+1 without whole genome duplication (WGD) and 10+2 with WGD. AmplificationTimeR takes data from Battenberg and DPClust preprocessing as input, along with a list of mutations. Timing can be done using clock-like mutations, or a list of provided mutations, which is recommended to only contain mutations attributed to clock-like mutational signatures.

AmplificationTimeR was published in Bioinformatics.