100,000 Genomes Project
The 100,000 Genomes project has whole-genome sequenced 25,000 cancers through Genomics England. Through the NIHR Oxford Biomedical Centre (BRC) Molecular Diagnostics theme, members of my research group are analysing the DNA sequences of colorectal, endometrial and testicular cancers from the 100,000 Genomes project, with the aim of extending the scope of precision medicine. Through the BRC, we are also using novel sequencing technologies to gain further insights into tumour heterogeneity.